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Research Advances

  • Powerful Sequencing Tool Helps Identify Infectious Diseases in Mali

    February 27, 2025 - A study in Bamako, Mali, used the advanced VirCapSeq-VERT sequencing tool to identify multiple viral infections in patients with unexplained fever. Conducted by the National Institute of Allergy and Infectious Diseases (NIAID), the study revealed over 40 percent of patients had coinfections, helping identify diseases like dengue, Zika, and HIV. The tool, combined with traditional methods, could improve diagnostics in resource-limited areas with high disease incidence, offering better patient outcomes.

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  • NIAID Study Describes Successful Treatment Regimen for Person With Multidrug-Resistant HIV

    January 16, 2025 - A National Institute of Allergy and Infectious Diseases (NIAID) study published in Nature Medicine describes a successful treatment regimen for a person with multidrug-resistant (MDR) HIV. The regimen included the investigational monoclonal antibody UB-421, along with antiretrovirals approved by the U.S. Food and Drug Administration (FDA), like lenacapavir. After 70 weeks of treatment, the patient’s HIV levels decreased significantly, and immune cell recovery was observed. This promising approach could offer new treatment options for those with limited alternatives due to MDR HIV.

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  • As Prevention Strategy for Sexually Transmitted Infections (STI) Rolls Out, Experts Highlight Both Promise and Knowledge Gaps

    January 6, 2025 - Doxycycline post-exposure prophylaxis has shown promise in reducing syphilis and chlamydia rates in some populations. However, it has had minimal impact on gonorrhea and may contribute to antibiotic resistance. Research highlights the need for continued monitoring. Experts also emphasize the importance of ensuring broad access and further investigation into long-term efficacy and alternative STI prevention strategies.

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This page last reviewed on March 26, 2025