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Notice of Special Interest (NOSI): Mental Health Comorbidities in HIV Prevention and Treatment

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Notice Special Interest NOSI): Mental Health Comorbidities HIV Prevention Treatment Notice Number: NOT-MH-20-013 Key Dates Release Date: March 30, 2020 First Available Due Date: 07, 2020 Expiration Date: 08, 2023 Related Announcements PA-20-144, Innovations HIV Prevention, Testing, Adherence Retention Optimize HIV Prevention Care Continuum Outcomes R01 Clinical Trial Optional) PA-20-145, Innovations HIV Prevention, Testing, Adherence Retention Optimize HIV Prevention Care Continuum Outcomes R21 Clinical Trial Optional) PA-20-141, Formative Pilot Intervention Research Prevention Treatment HIV/AIDS R34 Clinical Trial Optional) PA-19-126, Mentored Research Scientist Development Award Parent K01 - Independent Clinical Trial Allowed) PA-19-127, Mentored Research Scientist Development Award Parent K01 - Independent Clinical Trial Required) PA-19-116, Mentored Clinical Scientist Research Career Development Award Parent K08 Independent Clinical Trial Required) PA-19-117, Mentored Clinical Scientist Research Career Development Award Parent K08 Independent Clinical Trial Allowed) PA-19-118, Mentored Patient-Oriented Research Career Development Award Parent K23 Independent Clinical Trial Required) PA-19-119, Mentored Patient-Oriented Research Career Development Award Parent K23 – Independent Clinical Trial Allowed) PA-19-052, NIH Small Research Grant Program Parent R03 Clinical Trial Allowed) PA-19-129, NIH Pathway Independence Award Parent K99/R00 Independent Clinical Trial Required) PA-19-130, NIH Pathway Independence Award Parent K99/R00 - Independent Clinical Trial Allowed) PA-19-121, Midcareer Investigator Award Patient-Oriented Research Parent K24 Independent Clinical Trial Required) PA-19-122, Midcareer Investigator Award Patient-Oriented Research Parent K24 Independent Clinical Trial Allowed) PA-19-272, PHS 2019-02 Omnibus Solicitation the NIH, CDC, FDA Small Business Innovation Research Grant Applications Parent SBIR R43/R44] Clinical Trial Allowed) PA-19-273, PHS 2019-02 Omnibus Solicitation the NIH, CDC, FDA Small Business Innovation Research Grant Applications Parent SBIR R43/R44] Clinical Trial Required) PA-19-270, PHS 2019-02 Omnibus Solicitation the NIH Small Business Technology Transfer Grant Applications Parent STTR R41/R42] Clinical Trial Allowed PA-19-271, PHS 2019-02 Omnibus Solicitation the NIH Small Business Technology Transfer Grant Applications Parent STTR R41/R42] Clinical Trial Required PAR-19-051, Emerging Global Leader Award K43 Independent Clinical Trial Required) PAR-19-098, Emerging Global Leader Award K43 Independent Clinical Trial Allowed) PAR-17-485, NIMH Research Education Mentoring Program HIV/AIDS Researchers R25) PAR-18-714, Academic Research Enhancement Award Undergraduate-Focused Institutions R15 - Clinical Trial Allowed) PAR-19-133, Academic Research Enhancement Award Undergraduate-Focused Institutions R15 – Clinical Trial Required) PAR-19-134, Research Enhancement Award Program REAP) Health Professional Schools Graduate Schools R15 Clinical Trial Allowed) PAR-19-135, Research Enhancement Award Program REAP) Health Professional Schools Graduate Schools R15 Clinical Trial Required) PAR-19-283, Fogarty HIV Research Training Program Low-and Middle-Income Country Institutions D43 Clinical Trial Optional) PA-19-192, Ruth L. Kirschstein National Research Service Award NRSA) Individual Fellowship Students Institutions Without NIH-Funded Institutional Predoctoral Dual-Degree Training Programs Parent F30) PA-19-195, Ruth L. Kirschstein National Research Service Award NRSA) Individual Predoctoral Fellowship Parent F31) PA-19-196, Ruth L. Kirschstein National Research Service Award NRSA) Individual Predoctoral Fellowship Promote Diversity Health-Related Research Parent F31 Diversity) PA-19-188, Ruth L. Kirschstein National Research Service Award NRSA) Individual Postdoctoral Fellowship Parent F32) PA-18-403, Ruth L. Kirschstein National Research Service Award NRSA) Institutional Research Training Grant Parent T32) Issued National Institute Mental Health NIMH) Purpose National Institute Mental Health issuing Notice highlight interest receiving grant applications focused understanding addressing impact mental health comorbidities, including mental health disorders well violence trauma, the HIV prevention treatment continua. the U.S. globally, mental disorders prevalent among populations risk HIV acquisition transmission, well people living HIV PLHIV). Exposure violent traumatic events frequently comorbid mental health disorders, also impacts HIV prevention treatment continua. Mental disorders violence/trauma associated increased HIV acquisition transmission risk behaviors, they be barrier the uptake HIV prevention tools such HIV testing Pre-Exposure Prophylaxis PrEP), well HIV care treatment. are numerous evidence-based interventions improve mental health; however, are gaps our understanding how best address mental health comorbidities the context HIV prevention treatment. effect efficacious mental health interventions HIV prevention treatment outcomes mixed, efficacious mental health treatment need be combined effective HIV prevention care interventions maximally improve mental health HIV outcomes. populations, such perinatal women, unique biopsychosocial factors impact mental health, are understudied terms addressing mental health comorbidities improve HIV prevention treatment outcomes. Mental health comorbidities besides depression rarely addressed HIV research, despite high prevalence disorders such anxiety post traumatic stress people risk or living HIV. Despite high prevalence violence exposures among people risk or living HIV, are gaps our knowledge the mechanisms through violence impacts HIV prevention treatment continua; further, are few empirically based interventions address violence have shown improve HIV prevention treatment outcomes. is need deliver efficacious mental health violence/trauma-related treatments scalable cost-efficient ways. Deployment effective interventions depends upon number factors, including routine screening identify individuals mental disorders. Staffing systemic changes busy clinical settings be needed effective implementation mental health interventions. Targeted implementation science help answer key questions produce generalizable knowledge regarding feasible scalable approaches. Areas Research Interest Areas programmatic interest include, are limited to: Studies adapt test interventions designed improve mental health HIV prevention treatment outcomes, along examination potential mechanisms change. Studies adapt test interventions designed address violence trauma exposure improve HIV prevention treatment outcomes, along examination potential mechanisms change. Studies designed address mental health and/or trauma-related factors adversely impact mobile populations, such migrants, displaced people, individuals are homeless marginally housed, accessing benefitting HIV care prevention services. Studies evaluate differentiated models mental health trauma-related care those high risk HIV transmission acquisition living HIV experience mild mental disorder trauma symptoms versus those more severe symptoms diagnoses. Studies test approaches integrating screening mental health symptoms trauma/violence HIV prevention care, link or provide appropriate levels mental health/trauma-related care HIV prevention treatment. Studies develop innovative models integrated services improve HIV- mental health trauma-related outcomes, along examination change mechanisms. Studies test decision support tools help individuals, couples, providers informed choices utilize evidenced-based mental health/trauma HIV prevention treatment services. Studies examine impact changes policy/legislation affect delivery mental health trauma-related care HIV integration. Comparative effectiveness research determine relative effects interventions mental disorders violence/trauma HIV-related prevention treatment outcomes. Cost-effectiveness studies assess economic benefits interventions addressing mental health trauma/violence improve HIV prevention care outcomes. Studies designed enhance understanding identify modifiable targets provider, clinic systems-level factors may impact capacity implement evidence-based screening mental disorders trauma provision appropriate mental health/trauma services among persons highest risk HIV acquisition people living HIV. is strongly recommended applicants review NIMH Division AIDS Research current Funding Opportunity Announcements available our website at https://www.nimh.nih.gov/about/organization/dar/aids-related-funding-op…), consult a Program Officer before application submission. NIMH published updated policies guidance investigators regarding human research protection clinical research data safety monitoring NOT-MH-15-025). application’s Protection Human Subjects section data safety monitoring plans should reflect policies guidance this notice. Plans the protection research subjects data safety monitoring be reviewed the NIMH consistency NIMH NIH policies federal regulations. Application Submission Information notice applies due dates or after 7, 2020 subsequent receipt dates through 8, 2023. Submit applications this initiative using of following funding opportunity announcements FOAs) any reissues these announcement through expiration date this notice. PA-20-144, Innovations HIV Prevention, Testing, Adherence Retention Optimize HIV Prevention Care Continuum Outcomes R01 Clinical Trial Optional PA-20-145, Innovations HIV Prevention, Testing, Adherence Retention Optimize HIV Prevention Care Continuum Outcomes R21 Clinical Trial Optional PA-20-141, Formative Pilot Intervention Research Prevention Treatment HIV/AIDS R34 Clinical Trial Optional) PA-19-126, Mentored Research Scientist Development Award Parent K01 - Independent Clinical Trial Allowed) PA-19-127, Mentored Research Scientist Development Award Parent K01 - Independent Clinical Trial Required) PA-19-116, Mentored Clinical Scientist Research Career Development Award Parent K08 Independent Clinical Trial Required) PA-19-117, Mentored Clinical Scientist Research Career Development Award Parent K08 Independent Clinical Trial Allowed) PA-19-118, Mentored Patient-Oriented Research Career Development Award Parent K23 Independent Clinical Trial Required) PA-19-119, Mentored Patient-Oriented Research Career Development Award Parent K23 – Independent Clinical Trial Allowed) PA-19-052, NIH Small Research Grant Program Parent R03 Clinical Trial Allowed) PA-19-129, NIH Pathway Independence Award Parent K99/R00 Independent Clinical Trial Required) PA-19-130, NIH Pathway Independence Award Parent K99/R00 - Independent Clinical Trial Allowed) PA-19-121, Midcareer Investigator Award Patient-Oriented Research Parent K24 Independent Clinical Trial Required) PA-19-122, Midcareer Investigator Award Patient-Oriented Research Parent K24 Independent Clinical Trial Allowed) PA-19-272, PHS 2019-02 Omnibus Solicitation the NIH, CDC, FDA Small Business Innovation Research Grant Applications Parent SBIR R43/R44] Clinical Trial Allowed) PA-19-273, PHS 2019-02 Omnibus Solicitation the NIH, CDC, FDA Small Business Innovation Research Grant Applications Parent SBIR R43/R44] Clinical Trial Required) PA-19-270, PHS 2019-02 Omnibus Solicitation the NIH Small Business Technology Transfer Grant Applications Parent STTR R41/R42] Clinical Trial Allowed) PA-19-271, PHS 2019-02 Omnibus Solicitation the NIH Small Business Technology Transfer Grant Applications Parent STTR R41/R42] Clinical Trial Required) PAR-19-051, Emerging Global Leader Award K43 Independent Clinical Trial Required) PAR-19-098, Emerging Global Leader Award K43 Independent Clinical Trial Allowed) PAR-17-485, NIMH Research Education Mentoring Program HIV/AIDS Researchers R25) PAR-18-714, Academic Research Enhancement Award Undergraduate-Focused Institutions R15 - Clinical Trial Allowed) PAR-19-133, Academic Research Enhancement Award Undergraduate-Focused Institutions R15 – Clinical Trial Required) PAR-19-134, Research Enhancement Award Program REAP) Health Professional Schools Graduate Schools R15 Clinical Trial Allowed) PAR-19-135, Research Enhancement Award Program REAP) Health Professional Schools Graduate Schools R15 Clinical Trial Required) PAR-19-283, Fogarty HIV Research Training Program Low-and Middle-Income Country Institutions D43 Clinical Trial Optional) PA-19-192, Ruth L. Kirschstein National Research Service Award NRSA) Individual Fellowship Students Institutions Without NIH-Funded Institutional Predoctoral Dual-Degree Training Programs Parent F30) PA-19-195, Ruth L. Kirschstein National Research Service Award NRSA) Individual Predoctoral Fellowship Parent F31) PA-19-196, Ruth L. Kirschstein National Research Service Award NRSA) Individual Predoctoral Fellowship Promote Diversity Health-Related Research Parent F31 Diversity) PA-19-188, Ruth L. Kirschstein National Research Service Award NRSA) Individual Postdoctoral Fellowship Parent F32) PA-18-403, Ruth L. Kirschstein National Research Service Award NRSA) Institutional Research Training Grant Parent T32) instructions the SF424 R&R) Application Guide and funding opportunity announcement used submission must followed, the following additions: funding consideration, applicants must include NOT-MH-20-013” without quotation marks) the Agency Routing Identifier field box 4B) the SF424 R&R form. Applications without information box 4B not considered this initiative. Applications nonresponsive terms this NOSI be be considered the NOSI initiative.   Inquiries Please direct inquiries the contacts Section VII the listed funding opportunity announcements the following additions/substitutions: Scientific/Research Contact(s) Teri Senn, Ph.D. National Institute Mental Health NIMH) Telephone: 301-761-7852 Email: teri.senn@nih.gov Peer Review Contact(s) Examine eRA Commons account review assignment contact information information appears weeks after submission due date). Financial/Grants Management Contact(s) Rita Sisco National Institute Mental Health NIMH) Telephone: 301-443-2805 Email: siscor@mail.nih.gov    

Funding Number
NOT-MH-20-013
Funding Activity Code
05/08/2023
Release Date
Expiration Date
Organization
NIMH
Division
DCM

This page last reviewed on August 10, 2021